A 30-year-old woman was evaluated because of back pain, leg stiffness, and falling. Tone was increased in the legs.

One of the major determinants of exercise intolerance and limiting symptoms among patients with obstructive hypertrophic cardiomyopathy (HCM) is an elevated intracardiac pressure resulting from ...

The use of thrombectomy in patients with acute stroke and a large infarct of unrestricted size has not been well studied. We assigned, in a 1:1 ratio, patients with proximal cerebral vessel ...

In patients with immune thrombotic thrombocytopenic purpura (iTTP), autoantibodies against the metalloprotease ADAMTS13 lead to catastrophic microvascular thrombosis. However, the potential ...

A 47-year-old man was incidentally found to have diffuse nodular opacities on chest radiography. He had worked in a quarry for more than 30 years.

After Covid-19, the global health community must address major gaps in global preparedness, critical capacities needed for a safer and fairer world, and international instruments required for ...

“You don’t know what you’re missing till it’s gone” is a truism that certainly applies to taste. It took a pandemic for taste to get attention. Severe acute respiratory syndrome ...

In April 1964, leading cardiologists, cardiovascular surgeons, and pathologists convened in London for a 2-day symposium to discuss a relatively new disease entity that we now know as obstructive ...

Trials that showed a benefit of thrombectomy in stroke due to large-artery occlusion in the anterior circulation excluded patients with the largest infarcts. New research findings that include ...

A 62-year-old man presented with a 1-month history of muscle aches in the legs and weight loss. Abdominal angiography revealed aneurysms and irregularity of the walls of multiple arteries.

A pediatrician caring for patients with a rare and life-limiting disease learns from his mentor the benefits of acknowledging that his story and his patients’ stories are inextricably intertwined.