Frontiers24d
Identification of a novel ANK1 gene variant c.1504-9G>A and its mechanism of intron retention in hereditary spherocytosis
The red arrow highlights the mutation site confirmed by Sanger sequencing. The pcMINI-ANK1-wt/mut minigene construct was designed to incorporate a segment of intron 13 (397bp), exon 14 (198bp), and ...
The Straits Times27d
Berita Harian celebrates Hari Raya Aidilfitri with inaugural short film
SINGAPORE – Berita Harian (BH) has produced a short film, titled Pesan Mama (Mum’s Words), to celebrate Hari Raya Aidilfitri and to promote values of family and resilience. The seven-minute ...
eLife29d
A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence
This raises the possibility that transcriptional readthrough and intron retention are responsible for age-related changes in transposon expression rather than expression of autonomous transposons. To ...
eLife29d
A concerted increase in readthrough and intron retention drives transposon expression during aging and senescence
In this manuscript, the authors examined the role of transcription readout and intron retention in increasing transcription of transposable elements during aging in mammals. It is assumed that most ...